Mouse Secondary Antibodies
Biotium Human Kappa Light Chain (B-Cell Marker) (KLC1278), CF488A conjugate, 0.1mg/mL
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes l
Cayman Chemical ConcnavalIn A 100mg
A plant lectin with diverse biological activities; induces erythrocyte agglutination, mitogenic stimulation, and has anticancer activity; has been used in affinity purification of various glycoproteins, as well as to induce T cell activation in vitro and liver injury in experimental mouse models of autoimmune hepatitis
ABclonal Technology PE Mouse anti-Human CD56 mAb
This gene encodes a cell adhesion protein in the immunoglobulin superfamily involved in cell-to-cell and cell-matrix interactions during development It regulates neurogenesis neurite outgrowth and cell migration in the nervous system The protein also aids in the expansion of T lymphocytes B lymphocytes and natural killer (NK) cells essential for immune surveillance It interacts with fibroblast growth factor receptors and other extracellular matrix components triggering signaling pathways such as FYN-FAK MAPK and PI3K The CD56 isoform plays a role in myeloproliferative disorders like acute myeloid leukemia with its expression linked to disease progression and lower survival rates Increased CD56 expression is also associated with severe COVID-19 Alternative splicing results in multiple isoforms
Cayman Chemical Acorus calamus a-asron 1g
A component of certain essential oils used in traditional Chinese herbal medicine; carcinogenic, neuroprotective, and radioprotective in mice when given at 50 mg/kg; inhibits HMG-CoA reductase (IC50 = 3 mM); inhibits CYP2D6 and CYP3A4 (IC50 = 55.2 and 65.2 μg/ml, respectively)
Cayman Chemical Mouse ntIDYKDDDDK IgG EuW1 1mg
Antibody: Mouse mononcolonal anti-DYDDDK IgG (clone M2) Dye: Europium Chelate W-1024 Excitation max. λ: 340 nm Emission max. λ: 615 nm Uses: TR-FRET and High throughput screening (HTS) applications
Biotium Beta-2-Microglobulin (B2M)(246-E9.E7), CF594 conjugate, 0.1mg/mL
Beta-2 microglobulin is a component of the class I major histocompatibility complex (MHC I) where it functions in antigen processing and presentation. Involved in the presentation of peptide antigens to the immune system. Human Beta-2 microglobulin is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human Beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection. Clone 246 E9.E7 is the same as HLA.ABC.m2.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and
Sino Biological Mouse Anti-Human IgG Secondary Antibody (HRP), Mouse MAb
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, reconbinant human IgG.This antibody was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
Biotium EGFR (Epidermal Growth Factor Receptor)(F4), CF647 conjugate, 0.1mg/mL
This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Cayman Chemical EnramycIn A 10mg
A lipopeptide antibiotic; inhibits avian myeloblastosis virus reverse transcriptase by 50% at 10 UG/ml in a cell-free assay
Biotium Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) (IGHM/2559R), CF488A conjugate, 0.1mg/mL
This antibody recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.Primary antibodies are available purifi
Biotium Human Nuclear Antigen(NM106), CF740 conjugate, 0.1mg/mL
This MAb is an excellent marker for all nuclei in cells and tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells and may be used to stain the nuclei of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low a
Cayman Chemical a-KetoIsocaproIc AcIdodIum 5g
A metabolite of leucine catabolism; increases the production of reactive species and decreases the activity of mitochondrial complex I and complex II-III in the rat hippocampus at 4 µmol; urine levels are reduced in db/db diabetic mice compared with heterozygous db/m non-diabetic mice; accumulates in the tissues and body fluids of patients with maple syrup urine disease
Cayman Chemical Mouse ntI6HIS IgG EuW1024 50ug
Antibody: Mouse monoclonal anti-6xHistidine IgG, clone AD1.1.10 Dye: Europium Chelate W-1024 Excitation max. λ: 340 nm Emission max. λ: 615 nm Uses: TR-FRET and High throughput screening (HTS) applications